Hyperglycemia in pregnancy and developmental outcomes in children at 18-60 months of age: The PANDORA Wave 1 study

A Titmuss; A D'aprano; F Barzi; ADH Brown; A Wood; C Connors; JA Boyle; E Moore; K O'dea; J Oats; HD Mcintyre; P Zimmet; JE Shaw; ME Craig; LJ Maple-Brown

Journal article

Hyperglycemia in pregnancy and developmental outcomes in children at 18-60 months of age: The PANDORA Wave 1 study

A Titmuss, A D'aprano, F Barzi, ADH Brown, A Wood, C Connors, JA Boyle, E Moore, K O'dea, J Oats, HD Mcintyre, P Zimmet, JE Shaw, ME Craig, LJ Maple-Brown

Journal of Developmental Origins of Health and Disease | Published : 2022

DOI: 10.1017/S2040174422000101

Abstract

This study aimed to explore the association between hyperglycemia in pregnancy (type 2 diabetes (T2D) and gestational diabetes mellitus (GDM)) and child developmental risk in Europid and Aboriginal women. PANDORA is a longitudinal birth cohort recruited from a hyperglycemia in pregnancy register, and from normoglycemic women in antenatal clinics. The Wave 1 substudy included 308 children who completed developmental and behavioral screening between age 18 and 60 months. Developmental risk was assessed using the Ages and Stages Questionnaire (ASQ) or equivalent modified ASQ for use with Aboriginal children. Emotional and behavioral risk was assessed using the Strengths and Difficulties Questio..

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University of Melbourne Researchers

Anita D'Aprano Author

Jeremy Oats Author

Related Projects (1)

PREGNANCY AND NEONATAL DIABETES OUTCOMES IN REMOTE AUSTRALIA (PANDORA) COHORT

The PANDORA study is a longitudinal birth cohort study recruited from a clinical register of Northern Territory women with diabetes in pregn..

Grants

Awarded by Channel 7 Children's Research Foundation

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council of Australia (NHMRC Grant no. 1078333) and the Channel 7 Children's Research Foundation (#161329). AT was supported by a NHMRC Postgraduate Scholarship (#114760), RACP NHMRC Woolcock Scholarship and NHMRC Hot North PhD Completion Scholarship. LMB was supported by NHMRC Practitioner Fellowship no.1078477 and NHMRC Investigator Grant no. 1194698. JAB was supported by NHMRC Career Development Fellowship. JES was supported by NHMRC Fellowship no. 1079438. ADHB was supported by a Viertel Senior Medical Research Fellowship and an NHMRC Senior Research Fellowship no. 1137563. AW was supported by a NHMRC Postgraduate Scholarship. MC was supported by a NHMRC Practitioner fellowship no. 1136735. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.